石运伟
发布时间:2020-05-14   浏览次数:1404

石运伟 博士、副研究员。


 2012年于南京大学获生物学博士学位。

 2014年进入亚博赞助阿根廷球队神经再生重点实验室,主要从事血管新生调控和神经损伤与修复相关的机制研究。中国神经科学学会会员、江苏省发育生物学学会会员、江苏省神经科学会会员。主持、参与多项企业合作项目和纵向课题。讲授研究生《高级分子生物学》课程。

主要研究方向:

 1、生理和病理状态血管新生的遗传调控

 2、血管与神经互作机制

 3、血管与神经相关疾病防治活性物质的筛选及作用机理

承担项目:

 横向课题一:2018/08-2018/12,20万元,主持

 横向课题二:2018/09-2019/08,54万元,主持

 横向课题三:2018/09-2019/08,52万元,主持

 横向课题四:2017/02-2019/06,53万元,第二位

 国家自然科学基金面上项目:血管新生的遗传调控,2019-2022,60万元,第三位

 江苏省自然科学基金青年项目:血管新生的遗传调控,2012-2015,20万元,第二位

近五年发表的论文:

(1)Yunwei Shi(#), Xiaoning Wang(#), Yuanyuan Shi(#), Jie Zhang, Shuyong Zhao, Zhenhua Yin, Guangmin Xu, Xuchu Duan, Zhimou Guo(*), Xinmiao Liang(*), Dong Liu(*), Two compounds isolated from ganglioside GM1 promote angiogenesis in zebrafish, Journal of Cardiovascular Pharmacology, 2019, in press.

(2)Yunwei Shi(#), Xuchu Duan(#), Guangmin Xu(#), Xiaoning Wang, Guanyun Wei, Shikui Dong, Gangcai Xie(*), Dong Liu(*), A ribosomal DNA-hosted microRNA regulates zebrafish embryonic angiogenesis, Angiogenesis, 2019, DOI: https://doi.org/10.1007/s10456-019-09663-3.

(3)Lili Bao(#), Bo You(#), Si Shi, Ying Shan, Qicheng Zhang, Huijun Yue, Jie Zhang, Wei Zhang, Yunwei Shi, Yifei Liu, Xin Wang, Dong Liu(*), Yiwen You(*), Metastasis-associated miR-23a from nasopharyngeal carcinoma-derived exosomes mediates angiogenesis by repressing a novel target gene TSGA10, Oncogene, 2018, DOI: 10.1038/s41388-018-0183-6.

(4)Yunwei Shi(#), Xiaochuan Zhang(#), Chen Chen(#), Tang Miao, Zhiwei Wang, Xinmiao Liang(*), Ding Fei(*), Caiping Wang(*). Schisantherin A attenuates ischemia/reperfusion-induced neuronal injury in rats via regulation of TLR4 and C5aR1 signaling pathways. Brain, Behavior, and Immunity,2017, 66: 244~256.

(5)Caiping Wang(#), Yunwei Shi(#), Miao Tang, Xiaochuan Zhang, Yun Gu, Xinmiao Liang(*), Zhiwei Wang(*), Fei Ding(*). Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats. Molecular Neurobiology, 2017, 54(3): 2126~2142.

(6)Jie Gong(#), Xin Wang(#), Chenwen Zhu, Xiaohua Dong, Qinxin Zhang, Xiaoning Wang, Xuchu Duan, Fuping Qian, Yunwei Shi, Yu Gao, Qingshun Zhao(*), Renjie Chai(*), Dong Liu(*), Insm1a Regulates Motor Neuron Development in Zebrafish, Frontiers in Molecular Neuroscience, 2017, 10: 274.

(7)Xin Wang(#), Changchun Ling(#), Liping Li(#), Yinyin Qin, Jialing Qi, Xiaoyu Liu, Bo You, Yunwei Shi, Jie Zhang, Qiu Jiang, Hui Xu, Cheng Sun, Yiwen You, Renjie Chai(*), Dong Liu(*), MicroRNA-10a/10b represses a novel target gene mib1 to regulate angiogenesis, Cardiovascular Research, 2016, 110: 140-150.

(8)Yunwei Shi(#), Wei Yuan(#), Xin Wang, Jie Gong, Shunxing Zhu, Linlin Chai, Jialing Qi, Yinyin Qin, Yu Gao, Yuling Zhou, Xiaole Fan, Chunya Ji, Jiayi Wu, Zhiwei Wang, Dong Liu(*), Combretastatin a-4 efficiently inhibits angiogenesis and induces neuronal apoptosis in zebrafish, Scientific Reports, 2016, 6: 30189.

(9)Jialing Qi(#), Zhangji Dong(#), Yunwei Shi, Xin Wang, Yinyin Qin, Yongming Wang, Dong Liu(*), NgAgo-based fabp11a gene knockdown causes eye developmental defects in zebrafish, Cell Research, 2016, 26: 1349-1352.

(10)Qun E(#), Miao Tang(#), Xiaochuan Zhang, Yunwei Shi, Dandan Wang, Yun Gu, Shiying Li, Xinmiao Liang(*), Zhiwei Wang(*), Caiping Wang(*). Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells. Cell Biology International, 2015, 39(12): 1418-1424.

(11)Caiping Wang(#), Guicai Li(#), Yunwei Shi, Xiaochuan Zhang, Jianlong Li, Zhiwei Wang, Fei Ding(*), Xinmiao Liang(*). Neuroprotective effect of schizandrin A on oxygen and glucose deprivation/reperfusion-induced cell injury in primary culture of rat cortical neurons. Journal of Physiology and Biochemistry, 2014, 70(3): 735-747.

(12)Caiping Wang(#), Luzhong Zhang(#), Guicai Li, Yunwei Shi, Jianlong Li, Xiaochuan Zhang, Zhiwei Wang(*), Fei Ding(*), Xinmiao Liang(*). Mulberroside A protects against ischemic impairment in primary culture of rat cortical neurons after oxygen-glucose deprivation followed by reperfusion. Journal of Neuroscience Research, 2014, 92(7): 944-954.

(13)刘雪静,王雪雯,石运伟,王新,高煜,刘东,生长激素促进斑马鱼尾鳍的再生,中国实验动物学报,2019, 27(2):154-159.

(14)吕峰,石运伟,王新,刘东,严兴洪,microRNA-10a/b通过抑制Mib1调节 斑马鱼神经元的发育,中国细胞生物学学报,2017, 39(2):191-196.

(15)袁玮,浦超,Rupesh Puri,石运伟,王 新,李石营,刘东,Non-muscle Myosin II-A调节斑马鱼胚胎发育过程中肠内分泌细胞的极化,中国细胞生物学报,2015, 37(3):328-334.